1·
15 hours agoGoogle voice
- 576 Posts
- 10.9K Comments
Joined 2 years ago
Cake day: July 6th, 2023
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1·21 hours agoI’m on a all animal products diet for gut and health reasons. I started doing keto for hypertension, once that cleared up I found full carnivore much easier to maintain. The benefits to my health have been pretty amazing. If I cheat, or go off the food plan, I feel it pretty quickly.
If I eat something with sugar now, I can feel my heart rate increase. If I eat some plant products, I can feel my gut bloating.
It does make eating out a little tricky, but most restaurants have a good option on the menu (poached eggs, grilled chicken, etc)
https://www.dietdoctor.com/low-carb/salt-guide#medical-conditions
There is interesting published research on the benefits of salt. Salt isn’t the hypertension boogyman it’s been built up to be, the real hypertension culprit is the sugar and carbohydrates.
oh nice! how is it going? seeing results?
1·22 hours agoWhile there is literature on ketogenic diets and metal issues, I’ve never seen people report “keto calm” like the they do talk about carnivore calm.
500 would just become the new baseline, but i see your point.
Thank you for explaining it.
Is there a way to get lemmy-federate to refresh my instance? (i’m still trying to find all the communities that get unsubscribed)
agreed, its 100% a lemmy issue. Out of curiosity, why unsubscribe at all? What is the downside?
For example, when I first heard of lemmy-federate, I added the bot to my instance, and then i unsubscribed from lots of communities in my feed, assuming the bot would subscribe, and I could use “subscribe” like a normal user… but the bot didn’t subscribe, and i lost all those communities - unless i subscribed again.
Will the bot eventually subscribe again if the followers hit zero? I’ve waited 24 hours, and so far it hasn’t.
That’s literally what we are doing right now
Any way to force the federation of the unban later to get the instance to sync the current ban status?
I just wrote a script and iterated over the instance list from lemmy-explorer.
That’s a good idea! I tried that, but if your banned from a instance the mod log of that ban doesn’t federate back to my instance.
Example: https://lemm.ee/modlog?page=1&actionType=All&userId=1208549 vs https://sh.itjust.works/modlog?page=1&actionType=All&userId=1211562
The sh.itjust.works ban isn’t federated.
oh yeah! you have to be careful coming off a prolonged fast. glad you recovered!
1·3 days agoLooks like you have a 5 day water fast coming up!
Breakfast for dinner
The three most interesting figure from the paper.
They do break down the changes of various biomarkers of this group in table 2, its interesting
Noteworthy, the individuals who initially had pre-diabetic HbA1c values and high triglyceride levels were able to lower these atherosclerotic risk markers; however, because some individuals with initially low HbA1c or triglyceride values experienced an increase in HbA1c or triglycerides, respectively, the overall difference between pre-diet and on-diet values was not statistically significant
1·3 days agoI’m sure someone is working on a epidemiological association right now!
yes, I think so. Not locally, the whole body has to reduce the glucose and glutamine availability because everything is interconnected through the blood
https://hackertalks.com/post/8609461
Here is the proposed press-pulse protocol : https://pubmed.ncbi.nlm.nih.gov/28250801/ - Press-pulse: a novel therapeutic strategy for the metabolic management of cancer
Here is a application of that protocol for glioblastomas : https://pubmed.ncbi.nlm.nih.gov/39639257/ - Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
The press-pulse model shows lots of promise, and there are multiple ongoing studies with glioblastomas using this protocol.
Basically - deep ketosis, then periods of medicine to reduce glucose and glutamate
the TLDR here is they have quantified the energy consumption and fermentation of cancer cells and show that only glucose and glutamine can produce ATP in cancer cells. This has large implicates for cancer treatments.
Dr. Seyfried also has a conversational video talking about the paper https://www.youtube.com/watch?v=Pl5Nt3WrV5E
summerizer
In this video, Professor Seyfried discusses his recent paper that challenges long-standing assumptions in cancer treatment, specifically focusing on the Warburg hypothesis. He argues that many contemporary theories about cancer are based on misinterpretations of data from influential scientists like Otto Warburg and Sydney Weinhouse. Seyfried emphasizes that cancer is primarily a metabolic disease, driven by energy dysregulation instead of traditional genetic mutations. He introduces new insights into the role of mitochondrial function and the necessity of fermentable fuels like glucose and glutamine in cancer cell metabolism.
Key Points
Cancer Misunderstandings
Professor Seyfried outlines how modern cancer treatment theories derive from incorrect interpretations of ancient data, particularly misrepresenting the energy metabolism of cancer cells. He argues that this has led the cancer research field astray for decades.
Warburg Hypothesis Re-evaluated
Seyfried discusses the Warburg hypothesis, which posited cancer as a disorder of energy metabolism due to insufficient oxidative phosphorylation. He explains how earlier interpretations of data failed to acknowledge other forms of ATP production in cancer cells.
Oxygen Consumption vs ATP Production
The video highlights Seyfried’s findings that oxygen consumption does not accurately correlate with ATP production in cancer cells, as opposed to normal cells where oxygen consumption is an effective marker. This distinction is crucial for understanding cancer metabolism.
Mitigating Cancer Growth with Fuel Restrictions
Seyfried suggests a paradigm shift in cancer treatment—removing glucose and glutamine as energy sources—since these fuels drive cancer cell growth. He proposes ketogenic metabolic therapy as a more viable approach for managing cancer.
Mitochondrial Function in Cancer
The discussion emphasizes that cancer cells exhibit mitochondrial dysfunction, leading to altered energy production mechanisms and excessive lactic acid and lipid droplet accumulation. These abnormalities are signals of compromised oxidative phosphorylation capabilities.
Demand for New Cancer Treatment Models
Finally, Seyfried calls for a review of cancer treatment strategies based on understanding its metabolic origins rather than purely genetic approaches, asserting the need to develop management techniques that address the metabolic dysfunctions of tumors.
A self driving tool that can’t check blind spots but will do lane changes scares me